So the obese are still dying from Covid , big surprise.Obesity may weaken vaccine protection: Study
Author of the article:Reuters
Reuters
Nancy Lapid
Publishing date:May 06, 2022 • 16 hours ago • 3 minute read • Join the conversation
The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.
Obesity may weaken vaccine protection in the never infected
Severe obesity may weaken the effectiveness of COVID-19 vaccines in those who have never been infected with the coronavirus, according to a small Turkish study.
Among those in the study without previous SARS-CoV-2 infection who had received the Pfizer/BioNTech vaccine, patients with severe obesity had antibody levels more than three times lower than normal-weight individuals. Among recipients of Sinovac Biotech’s CoronaVac, those with severe obesity and no history of prior infection had antibody levels 27 times lower than normal weight people, according to data being presented this week at the European Congress on Obesity in Maastricht, Netherlands. By comparison, in the 70 volunteers with a previous coronavirus infection, antibody levels were similar in people with and without severe obesity.
For the study, researchers had compared immune responses to vaccines in 124 volunteers with severe obesity – defined as a body mass index of 40 or higher – and 166 normal-weight individuals (BMI less than 25). Overall, 130 participants had received two doses of the Pfizer/BioNTech mRNA vaccine and 160 had received two doses of Sinovac’s inactivated-virus vaccine.
While two doses of the Pfizer/BioNTech vaccine “may generate significantly more antibodies than CoronaVac in people with severe obesity… further research is needed to determine whether these higher antibody levels provide greater protection against COVID-19,” study leader Volkan Demirhan Yumuk from Istanbul University said in a statement
Unvaccinated Omicron patients at risk from variants
Infection with the Omicron variant of the coronavirus can significantly improve the immune system’s ability to protect against other variants, but only in people who have been vaccinated, South African researchers have found.
In unvaccinated people, an Omicron infection provides only “limited” protection against reinfection, they reported on Friday in Nature. In 39 patients who had Omicron infections – including 15 who had been immunized with vaccines from Pfizer/BioNTech or Johnson & Johnson – the researchers measured the ability of immune cells to neutralize not only Omicron but also earlier variants. At an average of 23 days after Omicron symptoms started, unvaccinated patients had 2.2-fold lower neutralization of the first version of the Omicron variant compared to vaccinated people, 4.8-fold lower neutralization of the second Omicron sublineage, 12-fold lower Delta neutralization, 9.6-fold lower Beta variant neutralization, and 17.9-fold lower neutralization of the original SARS-CoV-2 strain. The gap in immunity between unvaccinated and vaccinated individuals “is concerning,” the researchers said.
“Especially as immunity wanes, unvaccinated individuals post-Omicron infection are likely to have poor cross-protection against existing and possibly emerging SARS-CoV-2 variants,” they said. “The implication may be that Omicron infection alone is not sufficient for protection and vaccination should be administered even in areas with high prevalence of Omicron infection to protect against other variants.”
Different vaccines protect well against severe COVID-19
While the mRNA vaccines from Pfizer/BioNTech and Moderna generate higher antibody levels to protect against SARS-CoV-2 infection, AstraZeneca’s viral-vector-based vaccine provides equivalent protection against hospitalization and death from COVID-19, according a review of dozens of studies.
A panel of experts in Southeast Asia reviewed 79 previous studies for a study funded by AstraZeneca. Both types of vaccines showed over 90% efficacy against hospitalization and death, the panelists said in a report posted on Research Square ahead of peer review. “The high level of antibodies formed after the COVID-19 vaccination is often interpreted as the effectiveness of a vaccine. We now understand that while initial antibody response levels can vary across vaccines, their ability to prevent being hospitalized or dying from COVID-19 is equivalent,” panel member Dr. Erlina Burhan, a lung disease specialist at the University of Indonesia, in a statement.
A spokesperson for the panelists said the findings suggest decision-makers should use any vaccine type that is accessible and optimal for their local situation, and that people who have a choice of vaccine should know that the one they can get quickest is best.
A separate study published in Nature Communications found that while Moderna’s mRNA shots provide slightly more protection against coronavirus infection than the Pfizer/BioNTech vaccine, “there are no differences in vaccine effectiveness for protection against hospitalization, ICU admission, or death/hospice transfer.”
A Southeast Asia Expert Review of Global Real-World Vaccine Effectiveness Against SARS-CoV-2
BackgroundCOVID-19 vaccines have been highly effective in reducing morbidity and mortality during the pandemic. While primary series vaccination rates are generally high in Southeast Asian (SEA) countries, various factors have limited the rollout and impact of booster d...researchsquare.com
COVIDVACCINEPOSTER.pdf
drive.google.com
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Obesity may weaken vaccine protection: Study
Severe obesity may weaken the effectiveness of COVID-19 vaccines in those who have never been infected with the virus, says a small study.torontosun.com
that too.Maybe the vaccines just don't work as advertised?
with food shortages perhaps its for the best.So the obese are still dying from Covid , big surprise.
Maybe with green blood you can get carbon credits.
1million covid deaths equates to about .3% of the population. Much less depending on how many were about to die anyway and covid was just the last nail in the coffin.COVID-19 claims 1 million U.S. lives, leaving trail of loss
It represents about one death for every 327 Americans, or more than the entire population of San Francisco or Seattle.
Author of the article:Reuters
Reuters
Maria Caspani
Publishing date:May 11, 2022 • 12 hours ago • 3 minute read • Join the conversation
NEW YORK — The United States has now recorded more than 1 million COVID-19 deaths, according to a Reuters tally, crossing a once-unthinkable milestone about two years after the first cases upended everyday life and quickly transformed it.
The 1 million mark is a stark reminder of the staggering grief and loss caused by the pandemic even as the threat posed by the virus wanes in the minds of many people. It represents about one death for every 327 Americans, or more than the entire population of San Francisco or Seattle.
By the time the World Health Organization (WHO) declared COVID-19 a global pandemic on March 11, 2020, the virus had claimed 36 lives in the United States. In the months that followed, the deadly virus spread like wildfire, finding fertile ground in densely populated urban areas such as New York City and then reaching every corner of the country.
By June 2020, the U.S. death toll had surpassed the total of the country’s military deaths in the First World War and it would exceed the American military losses of the Second War World by January 2021 when more than 405,000 deaths were recorded.
The disease has left few places on Earth untouched, with 6.7 million confirmed deaths globally. The true toll, including those who died of COVID-19 as well as those who perished as an indirect result of the outbreak, was likely closer to 15 million, the WHO said.
Some of the images associated with COVID death are forever burned in the collective mind of Americans: refrigerated trucks stationed outside hospitals overflowing with the dead; intubated patients in sealed-off intensive care units; exhausted doctors and nurses who battled through every wave of the virus.
Millions of Americans eagerly rolled up their sleeves to receive COVID vaccines after distribution began in late 2020. By early 2021, the virus had already claimed a staggering 500,000 lives.
At one point in January of that year, more people died from COVID-19 every day on average than were killed in the Sept. 11 attacks in 2001.
COVID-19 preyed on the elderly and those with compromised health, but it did not spare healthy youth either, killing more than 1,000 children. Researchers estimate 213,000 U.S. children lost at least one parent or primary caregiver during the pandemic, taking an immeasurable emotional toll.
While nestling in big cities, coronavirus has also ravaged rural communities with limited access to medical care.
The pandemic had a disproportionate impact on native communities and communities of color. It hit harder where people lived in congregate settings, such as prisons, and decimated entire families. It exposed inequalities deeply entrenched in U.S. society and set off a wave of change affecting most aspects of life in the United States.
With the COVID-19 threat subsiding after the Omicron wave last winter, many Americans have shed masks and returned to offices in recent weeks. Restaurants and bars are once again teeming with patrons, and the public’s attention has shifted to inflation and economic concerns.
But researchers are already working on yet another booster shot as the virus continues to mutate.
“By no means is it over,” said top U.S. infectious disease expert Dr. Anthony Fauci at a recent event. “We still are experiencing a global pandemic.”
TRACKING THE PANDEMIC
Tracking the COVID-19 pandemic is not an exact science. Reuters and the other organizations who make tallies are reaching 1 million U.S. deaths at different times. The variation is due to how each organization counts COVID deaths. For example, Reuters includes both confirmed and probable deaths where that data is available.
The precise toll of the pandemic may never be truly known. Some people who died while infected were never tested and do not appear in the data. Others, while having COVID-19, may have died for another reason, such as a cancer, but were still counted.
The CDC estimates that 1.1 million excess deaths have taken place since Feb. 1, 2020, mainly from COVID. Excess mortality is the increase in total number of deaths, from any cause, compared with previous years.
You can read more about the Reuters methodology for tracking COVID cases and deaths here:
You can find more information on CDC excess deaths here:![]()
Coronavirus around the world: the latest counts, charts and maps
Tracking the global COVID-19 outbreak, updated dailygraphics.reuters.com
Excess Deaths Associated with COVID-19
Figures present excess deaths associated with COVID-19 at the national and state levels.cdc.gov
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COVID-19 Orphanhood Calculator
Global minimum estimates of children affected by COVID-19-associated orphanhood and deaths of caregiversimperialcollegelondon.github.io
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A million lives lost
Two years into the COVID pandemic, the U.S. is grieving a once unthinkable death toll.reuters.com
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COVID-19 claims 1 million U.S. lives, leaving trail of loss
The United States has now recorded more than 1 million COVID-19 deaths, according to a Reuters tally.torontosun.com