Omicron

Ron in Regina

"Voice of the West" Party
Apr 9, 2008
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Regina, Saskatchewan
Both vaccines are only offered as a booster dose, so only people who have already completed a primary series of a COVID-19 vaccine are eligible to receive them.

WHAT IS THE DIFFERENCE BETWEEN THE MODERNA AND PFIZER BIVALENT BOOSTERS?

There are a few slight differences between the two vaccines, explains Kelly Grindrod, who is a researcher and professor of pharmacy innovation at the Ontario College of Pharmacists.

"Moderna and Pfizer are fairly similar," Grindrod told CTVNews.ca in an email on Friday.

"The Moderna vaccine has a slightly higher dose and is based on the original virus and the Omicron BA1 variant. Pfizer is a slightly lower dose and is based on the original virus and the Omicron BA4 and BA5 variants."

COVID-19 moved at a rapid pace after Omicron surfaced in the United States toward the end of 2021 and spread like wildfire. Since then, multiple Omicron subvariants have emerged—a strain called BA.5 remains the predominant one in the U.S., making up 62% of infections in October 2022, while its close cousin, BA.4.6 made up 11% of cases. Early studies suggested Omicron appears to be milder than previous strains, although some experts have attributed this to the fact that many more people were vaccinated, and some had immunity from infection.

As winter approaches, it’s hard to predict whether there will be a new wave of COVID-19 cases. But experts are now monitoring more than 300 other descendants of Omicron around the world, including BQ.1 and BQ.1.1, subvariants of BA.5 that experts are still learning about and that have been spreading through Europe. In October, they accounted for more than 16% of cases in the U.S.
I got the damn flu from being in the hospital. It made recovery a real bitch.
Raw deal.
 

spaminator

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Oct 26, 2009
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After a year, omicron still driving COVID surges and worries
Author of the article:Associated Press
Associated Press
Laura Ungar
Publishing date:Nov 25, 2022 • 1 day ago • 5 minute read

A year after omicron began its assault on humanity, the ever-morphing coronavirus mutant drove COVID-19 case counts higher in many places just as Americans gathered for Thanksgiving. It was a prelude to a wave that experts expect to soon wash over the U.S.


Phoenix-area emergency physician Dr. Nicholas Vasquez said his hospital admitted a growing number of chronically ill people and nursing home residents with severe COVID-19 this month.


“It’s been quite a while since we needed to have COVID wards,” he said. “It’s making a clear comeback.”

Nationally, new COVID cases averaged around 39,300 a day as of Tuesday — far lower than last winter but a vast undercount because of reduced testing and reporting. About 28,000 people with COVID were hospitalized daily and about 340 died.

Cases and deaths were up from two weeks earlier. Yet a fifth of the U.S. population hasn’t been vaccinated, most Americans haven’t gotten the latest boosters and many have stopped wearing masks.


Meanwhile, the virus keeps finding ways to avoid defeat.

The omicron variant arrived in the U.S. just after Thanksgiving last year and caused the pandemic’s biggest wave of cases. Since then, it has spawned a large extended family of sub-variants, such as those most common in the U.S. now: BQ.1, BQ.1.1 and BA.5. They edged out competitors by getting better at evading immunity from vaccines and previous illness — and sickening millions.

Carey Johnson’s family got hit twice. She came down with COVID-19 in January during the first omicron wave, suffering flu-like symptoms and terrible pain that kept her down for a week. Her son Fabian Swain, 16, suffered much milder symptoms in September when the BA.5 variant was dominant.


Fabian recovered quickly, but Johnson had a headache for weeks. Other problems lingered longer.

“I was like, ‘I cannot get it together.’ I could not get my thoughts together. I couldn’t get my energy together” said Johnson, 42, of Germantown, Maryland. “And it went on for months like that.”

HOT SPOTS EMERGE

Some communities are being particularly hard hit right now. Tracking by the Mayo Clinic shows cases trending up in states such as Florida, Arizona, Colorado and New Mexico.

In Arizona’s Navajo County, the average daily case rate is more than double the state average. Dr. James McAuley said 25 to 50 people a day are testing positive for the coronavirus at the Indian Health Service facility where he works. Before, they saw just a few cases daily.


McAuley, clinical director of the Whiteriver Indian Hospital, which serves the White Mountain Apache Tribe, said they are “essentially back to where we were with our last big peak” in February.

COVID-19 is part of a triple threat that also includes flu and the virus known as RSV.

Dr. Vincent Hsu, who oversees infection control for AdventHealth, said the system’s pediatric hospital in Orlando is nearly full with kids sickened by these viruses. Dr. Greg Martin, past president of the Society of Critical Care Medicine, sees a similar trend elsewhere.

Pediatric hospitals’ emergency departments and urgent care clinics are busier than ever, said Martin, who practices mostly at Grady Memorial Hospital in Atlanta. “This is a record compared to any month, any week, any day in the past,” he said.


Looking to the future, experts see the seeds of a widespread U.S. wave. They point to what’s happening internationally — a BA.5 surge in Japan, a combination of variants pushing up cases in South Korea, the start of a new wave in Norway.

Some experts said a U.S. wave could begin during the holidays as people gather indoors. Trevor Bedford, a biologist and genetics expert at the Fred Hutchinson Cancer Research Center, said it could peak at around 150,000 new cases a day, about what the nation saw in July.

A new wave would be rough, said Dr. Mark Griffiths, medical director of the emergency department of Children’s Health Care of Atlanta-Spalding Hospital. “So many systems are on the brink of just being totally overburdened that if we get another COVID surge on top of this, it’s going to make some systems crack.”


One bright spot? Deaths are likely to be much lower than earlier in the pandemic. About 1 in 2,000 infections lead to death now, compared with about 1 in 200 in the first half of 2020, Bedford said.

OMICRON’S YEARLONG REIGN

The same widespread immunity that reduced deaths also pushed the coronavirus to mutate. By the end of last year, many people had gotten infected, vaccinated or both. That “created the initial niche for omicron to spread,” Bedford said, since the virus had significantly evolved in its ability to escape existing immunity.

Omicron thrived. Mara Aspinall, who teaches biomedical diagnostics at Arizona State University, noted that the first omicron strain represented 7.5% of circulating variants by mid-December and 80% just two weeks later. U.S. cases at one point soared to a million a day. Omicron generally caused less severe disease than previous variants, but hospitalizations and deaths shot up given the sheer numbers of infected people.


The giant wave ebbed by mid-April. The virus mutated quickly into a series of sub-variants adept at evading immunity. A recent study in the journal Science Immunology says this ability to escape antibodies is due to more than 30 changes in the spike protein studding the surface of the virus.

Omicron evolved so much in a year, Bedford said, it’s now “a meaningless term.”

That rapid mutation is likely to continue.

“There’s much more pressure for the virus to diversify,” said Shishi Luo, head of infectious diseases for Helix, a company that supplies viral sequencing information to the U.S. Centers for Disease Control and Prevention.

Doctors said the best protection against the bubbling stew of sub-variants remains vaccination. And officials said Americans who got the new combination booster targeting omicron and the original coronavirus are currently better protected than others against symptomatic infection.


Dr. Peter Hotez, co-director of the Center for Vaccine Development at Texas Children’s Hospital, said getting the booster, if you’re eligible, is “the most impactful thing you could do.”

Doctors also urge people to continue testing, keep up preventive measures such as masking in crowds, and stay home when sick.

“COVID is still a very significant threat, especially to the most vulnerable,” said Dr. Laolu Fayanju of Oak Street Health in Cleveland, which specializes in caring for older adults. “People have to continue to think about one another. We’re not completely out of the woods on this yet.”
 

Twin_Moose

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spaminator

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What do we know about COVID variant XBB.1.5?
Author of the article:Reuters
Reuters
Gabrielle Tétrault-Farber and Jennifer Rigby
Published Jan 05, 2023 • 3 minute read

GENEVA — The Omicron subvariant, XBB.1.5, is causing concern among scientists after its rapid spread in the United States in December. Several cases of the COVID-19 subvariant have also been detected in Canada.


Here is what we know so far:


WHAT IS THE XBB.1.5 SUBVARIANT AND HOW DOES IT BEHAVE?
The World Health Organization’s senior epidemiologist Maria Van Kerkhove said XBB.1.5 is the most transmissible Omicron sub-variant that has been detected so far. It spreads rapidly because of the mutations it contains, allowing it to adhere to cells and replicate easily.

“Our concern is how transmissible it is,” Van Kerkhove said in a news briefing on Wednesday.

XBB and XBB.1.5 were estimated to account for 44.1% of COVID-19 cases in the United States in the week of Dec. 31, up from 25.9% in the previous week, according to data from the U.S. Centers for Disease Control and Prevention. It has also been detected in 28 other countries worldwide, the WHO said.


XBB.1.5 is yet another descendant of Omicron, the most contagious variant of the virus causing COVID-19 that is now globally dominant. It is an offshoot of XBB, first detected in October, which is itself a recombinant of two other Omicron sub-variants.

HOW DANGEROUS IS XBB.1.5?
The WHO said it does not have any data on severity yet, or a clinical picture on its impact. It said that it saw no indication that its severity had changed but that increased transmissibility is always a concern.

“We do expect further waves of infection around the world, but that doesn’t have to translate into further waves of death because our countermeasures continue to work,” said Van Kerkhove, referring to vaccines and treatments.

She said the WHO was unable to currently attribute the increase in hospitalizations in the northeastern United States to the variant, given that many other respiratory viruses were also in circulation.


Virologists agree that the emergence of the new subvariant does not mean there is a new crisis in the pandemic. New variants are to be expected as the virus continues to spread.

XBB.1.5 is likely to spread globally, but it remains unclear if it will cause its own wave of infections around the world. Current vaccines continue to protect against severe symptoms, hospitalization and death, the experts say.

“There is no reason to think that XBB.1.5 is of any more concern than other variants that come and go in the ever-changing landscape of COVID-19 mutants,” said Professor Andrew Pollard, director of the Oxford Vaccine Group.

WHAT IS THE WHO DOING ABOUT IT?
The WHO’s Technical Advisory Group on Virus Evolution is doing a risk assessment on the subvariant. Van Kerkhove said on Wednesday it hoped to publish that in the next few days.


Professor Tulio de Oliveira, a South African scientist who sits on the committee, said the situation was “complex,” particularly given the global context of the surge of cases in China after it dropped its zero-COVID policy in December.

The WHO said it was closely monitoring any possible changes in the severity of the subvariant with the help of laboratory studies and real world data.




 

spaminator

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Oct 26, 2009
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New COVID strain a 'wakeup call': Experts
Author of the article:Kevin Connor
Published Jan 08, 2023 • 2 minute read

A new COVID strain called the Kraken is becoming a worry around the world.


XBB.1.5, a subvariant of Omicron, is now dominant in parts of the U.S. and it has started to gain ground in the U.K.


The U.K. Daily Mail says a contagious COVID strain has emerged and is behind three in four cases in the U.S.

The highly contagious COVID strain is already behind one in 25 cases in the U.K., data shows.

Experts say the new variant is a “wakeup call.”

The Sanger Institute, one of the U.K.’s largest COVID surveillance centres, shows four per cent of cases in the week to Dec. 17 were caused by XBB.1.5.

XBB.1.5 is a mutated version of Omicron XBB, a strain that was first found in India in August.

Its parent strain, XBB, caused cases to quadruple in just one month in some parts of the world.

Concern about XBB.1.5 is largely based on how it is currently surging in the U.S.


Statistics from the U.S. Centers for Disease Control and Prevention showed the strain is behind 41 % of cases.

The figure is up from 22% one week earlier.

XBB.1.5 has also been detected in countries including France, Germany, the Netherlands, Spain, Ireland, Australia, Singapore and India.

Professor Lawrence Young, a virologist at Warwick University, told the Daily Mail that the emergence of the strain could exacerbate the crisis in Britain.

“The XBB.1.5 variant is highly infectious and is driving increased hospital admissions in New York, particularly among the elderly,” Young said.

“Waning immunity, more indoor mixing because of the cold weather and lack of other mitigations, such as wearing facemasks, are also contributing to this surge of infection in the U.S.”

Public Health Ontario hasn’t yet found any XBB.1.5 cases.

“We have confirmed with our laboratory that, though we have not yet specifically reported cases of XBB.1.5 in Ontario, if there are any cases, they are currently being captured under XBB.1. The Ontario COVID-19 Genomics Network is in the process of updating the software used to assign lineages. Once updated, we will be able to identify XBB.1.5 cases specifically and reclassify any cases previously captured as XBB.1,” PHO said in a statement.
 

petros

The Central Scrutinizer
Nov 21, 2008
113,351
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Low Earth Orbit
New COVID strain a 'wakeup call': Experts
Author of the article:Kevin Connor
Published Jan 08, 2023 • 2 minute read

A new COVID strain called the Kraken is becoming a worry around the world.


XBB.1.5, a subvariant of Omicron, is now dominant in parts of the U.S. and it has started to gain ground in the U.K.


The U.K. Daily Mail says a contagious COVID strain has emerged and is behind three in four cases in the U.S.

The highly contagious COVID strain is already behind one in 25 cases in the U.K., data shows.

Experts say the new variant is a “wakeup call.”

The Sanger Institute, one of the U.K.’s largest COVID surveillance centres, shows four per cent of cases in the week to Dec. 17 were caused by XBB.1.5.

XBB.1.5 is a mutated version of Omicron XBB, a strain that was first found in India in August.

Its parent strain, XBB, caused cases to quadruple in just one month in some parts of the world.

Concern about XBB.1.5 is largely based on how it is currently surging in the U.S.


Statistics from the U.S. Centers for Disease Control and Prevention showed the strain is behind 41 % of cases.

The figure is up from 22% one week earlier.

XBB.1.5 has also been detected in countries including France, Germany, the Netherlands, Spain, Ireland, Australia, Singapore and India.

Professor Lawrence Young, a virologist at Warwick University, told the Daily Mail that the emergence of the strain could exacerbate the crisis in Britain.

“The XBB.1.5 variant is highly infectious and is driving increased hospital admissions in New York, particularly among the elderly,” Young said.

“Waning immunity, more indoor mixing because of the cold weather and lack of other mitigations, such as wearing facemasks, are also contributing to this surge of infection in the U.S.”

Public Health Ontario hasn’t yet found any XBB.1.5 cases.

“We have confirmed with our laboratory that, though we have not yet specifically reported cases of XBB.1.5 in Ontario, if there are any cases, they are currently being captured under XBB.1. The Ontario COVID-19 Genomics Network is in the process of updating the software used to assign lineages. Once updated, we will be able to identify XBB.1.5 cases specifically and reclassify any cases previously captured as XBB.1,” PHO said in a statement.
What happened to two shots and you'll have zero issues forever and ever Amen?
 

Ron in Regina

"Voice of the West" Party
Apr 9, 2008
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Regina, Saskatchewan
What happened to two shots and you'll have zero issues forever and ever Amen?

This is from the Gov’t site:
Doses of the COVID-19 vaccines received after the primary series are called booster doses. Booster doses restore protection from a primary series that may have decreased over time.

Booster doses increase your defences by activating your immune response to restore protection that may have decreased over time. They improve protection against severe outcomes and may also reduce the risk of post COVID-19 condition.

If it's been 6 months or longer since your last vaccine dose or COVID-19 infection, get a booster dose by contacting your province or territory or health care provider.
 

Tecumsehsbones

Hall of Fame Member
Mar 18, 2013
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This is from the Gov’t site:
Doses of the COVID-19 vaccines received after the primary series are called booster doses. Booster doses restore protection from a primary series that may have decreased over time.

Booster doses increase your defences by activating your immune response to restore protection that may have decreased over time. They improve protection against severe outcomes and may also reduce the risk of post COVID-19 condition.

If it's been 6 months or longer since your last vaccine dose or COVID-19 infection, get a booster dose by contacting your province or territory or health care provider.
Nope. 100% effectiveness on a crash program to produce a vaccine in record time or it's WORTHLESS! And NEFARIOUS! And unAMER. . . um. . . unCANADIAN!
 

Tecumsehsbones

Hall of Fame Member
Mar 18, 2013
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Yep, because once you get vaccinated for something, you never need new updates ever again.
Damn straight! Got me a flu shot in '72, and I still get the flu most every year.

Clearly the Nixon gummint's just trying to TAKE AWAY MY FREEDOM and ENSLAVE ME!

Now that I'm a mite long in the tooth to be a child sex slave. . .
 
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Reactions: Serryah

Serryah

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Dec 3, 2008
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New Brunswick
Damn straight! Got me a flu shot in '72, and I still get the flu most every year.

Clearly the Nixon gummint's just trying to TAKE AWAY MY FREEDOM and ENSLAVE ME!

Now that I'm a mite long in the tooth to be a child sex slave. . .

Just don't need a tetanus shot cause that's one of those vaccine things too you need to boost.
 

petros

The Central Scrutinizer
Nov 21, 2008
113,351
12,818
113
Low Earth Orbit

This is from the Gov’t site:
Doses of the COVID-19 vaccines received after the primary series are called booster doses. Booster doses restore protection from a primary series that may have decreased over time.

Booster doses increase your defences by activating your immune response to restore protection that may have decreased over time. They improve protection against severe outcomes and may also reduce the risk of post COVID-19 condition.

If it's been 6 months or longer since your last vaccine dose or COVID-19 infection, get a booster dose by contacting your province or territory or health care provider.

 

petros

The Central Scrutinizer
Nov 21, 2008
113,351
12,818
113
Low Earth Orbit
Data on the clinical efficacy of bivalent vaccines from randomized controlled trials are lacking. Nevertheless, preliminary evidence from the US indicates significant protection with bivalent boosters against severe illness, with efficacy estimates ranging between 38% and 73%. Still, the effectiveness of bivalent boosters in preventing COVID-19 hospitalization and mortality remains unknown.