My feeling is that if Quebec wants to go, let her. All I know is that I would hope that the federal gov't make it crystal clear that they absorb their portion of the debt, they use their own currency, transfer payments cease at once and as ruled by the Supreme Court in 1995, the borders are not static. Seperatists need to know that we are adamant on this. They will also have to negotiate with Ottawa the purchase any federal assets within the decided borders of Quebec. Under that scenario, they'll be "in hock" for many centuries!!
But what about the Quebecers who don't want to separate? Do Canadians really want to throw them out as well? That is part of my conundrum, for sure.
I'm betting that the Cree will likely have something to say about the whole separation issue and its unlikely that Quebec would be able to negotiate anything without their consent.
Bottom line - I would 'prefer' Quebec in Canada (albeit a more appreciative/happier Quebec) but we can survive without them too.
JMHO