Yes, in reality there are people named Sammy, Bobby, and Dean, and maybe people named Castiel since that character appeared in popular culture,there are black 1967 Chevrolet Impalas with big engines and noisy mufflers, there are people who try to help and people who try to hurt, and there is tension, conflict, drama, a lot of good people and a lot of bad people. What there are not in reality are angels, demons, gods, devils, people who hunt and kill them, heaven, hell, or supernatural powers, beings, or places, of any kind, there's no good reason to think any of those exist. The TV series is in the horror/fantasy category, it makes no claims about being right or wrong about anything. It's just entertainment, and very good entertainment too in my not very humble opinion, with well developed characters, good stories well told, and great background music. "Carry On My Wayward Son" is one of the great rock songs of all time. H.P. Lovecraft would have loved it all.