Quote: Originally Posted by YukonJack
For years I had horrible shoulder pains. Tried T3, Naproxen followed by Dilaudil.
Until a rheumatologist prescribed Sulfasalazine, which got me totally pain-free.
Smoking dope? Never occured to me. It's only for dopes.
you only say that because of what you read/heard about it via the media.
side effects of sulfasalazine...........This medication may cause stomach upset, diarrhea, nausea, vomiting, headache (external - login to view)
, drowsiness, dizziness or trouble sleeping during the first few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor. May cause urine to be orange-brown in color. This is not harmful and will disappear when the medication is stopped. This medication increases sensitivity to sunlight. Notify your doctor if your condition worsens or you develop: easy bruising. Rarely, this medication can cause serious, even fatal, side effects such as a severe peeling skin rash (external - login to view)
known as Stevens- Johnson syndrome, blood disorders (e.g., agranulocytosis, aplastic anemia (external - login to view)
), or liver damage. Seek immediate medical attention if you develop any of the following symptoms: skin rash or blisters, unusual fatigue, persistent sore throat (external - login to view)
or fever, yellowing eyes or skin, dark urine, abdominal pain (external - login to view)
. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
SULFASALAZINE - ORAL (Azulfidine) side effects, medical uses, and drug interactions. (external - login to view)
Carcinogenesis, Mutagenesis, Impairment of Fertility
Two-year oral carcinogenicity studies were conducted in male and female F344/N rats and B6C3F1 mice. Sulfasalazine was tested at 84 (496 mg/m2), 168 (991 mg/m2), and 337.5 (1991 mg/m2) mg/kg/day doses in rats. A statistically significant increase in the incidence of urinary bladder transitional cell papillomas was observed in male rats. In female rats, two (4%) of the 337.5 mg/kg rats had transitional cell papilloma of the kidney. The increased incidence of neoplasms in the urinary bladder and kidney of rats was also associated with an increase in the renal calculi formation and hyperplasia of transitional cell epithelium. For the mouse study, Sulfasalazine was tested at 675 (2025 mg/m2), 1350 (4050 mg/m2), and 2700 (8100 mg/m2) mg/kg/day. The incidence of hepatocellular adenoma or carcinoma in male and female mice was significantly greater than the control at all doses tested.
Sulfasalazine did not show mutagenicity in the bacterial reverse mutation assay (Ames test) and in L51784 mouse lymphoma cell assay at the HGPRT gene. However, Sulfasalazine showed equivocal mutagenic response in the micronucleus assay of mouse and rat bone marrow and mouse peripheral RBC and in the sister chromatid exchange, chromosomal aberration, and micronucleus assays in lymphocytes obtained from humans.
Impairment of male fertility was observed in reproductive studies performed in rats at a dose of 800 mg/kg/day (4800 mg/m2). Oligospermia and infertility have been described in men treated with Sulfasalazine. Withdrawal of the drug appears to reverse these effects.
Read more: Sulfasalazine Official FDA information, side effects and uses. (external - login to view)
I know which I'd prefer to take for pain relief and it wouldnt be some concoction created in a lab. I prefer the natural way myself and to date havent noticed any side effects................
Last edited by Stretch; Aug 3rd, 2010 at 06:31 PM..