...or, the tongue-in-cheek farkish headline:
6'4" DNA researchers with full heads of hair, muscular builds, sculpted jawlines and piercing blue eyes say that they've discovered a way to edit any DNA sequence at will
Scientists at The Scripps Research Institute (TSRI) have found a way to apply a powerful new DNA-editing technology more broadly than ever before. “This is one of the hottest tools in biology, and we’ve now found a way to target it to any DNA sequence,” said Carlos F. Barbas III, the Janet and Keith Kellogg II Chair in Molecular Biology and Professor in the Department of Chemistry at TSRI. The breakthrough concerns a set of designer DNA-binding proteins called TALEs, which biologists increasingly use to turn on, turn off, delete, insert or even rewrite specific genes within cells—for scientific experiments and also for potential biotech and medical applications, including treatments for genetic diseases. TALE-based methods had been considered useful against only a fraction of the possible DNA sequences found in animals and plants, but the new finding removes that limitation. Barbas and his team report their finding on August 26, 2013 in an advance online edition of the journal Nucleic Acids Research ("Directed evolution of the TALE N-terminal domain for recognition of all 5' bases").
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Scientists report breakthrough in DNA editing technology
6'4" DNA researchers with full heads of hair, muscular builds, sculpted jawlines and piercing blue eyes say that they've discovered a way to edit any DNA sequence at will
Scientists at The Scripps Research Institute (TSRI) have found a way to apply a powerful new DNA-editing technology more broadly than ever before. “This is one of the hottest tools in biology, and we’ve now found a way to target it to any DNA sequence,” said Carlos F. Barbas III, the Janet and Keith Kellogg II Chair in Molecular Biology and Professor in the Department of Chemistry at TSRI. The breakthrough concerns a set of designer DNA-binding proteins called TALEs, which biologists increasingly use to turn on, turn off, delete, insert or even rewrite specific genes within cells—for scientific experiments and also for potential biotech and medical applications, including treatments for genetic diseases. TALE-based methods had been considered useful against only a fraction of the possible DNA sequences found in animals and plants, but the new finding removes that limitation. Barbas and his team report their finding on August 26, 2013 in an advance online edition of the journal Nucleic Acids Research ("Directed evolution of the TALE N-terminal domain for recognition of all 5' bases").
more
Scientists report breakthrough in DNA editing technology