Speaking in the City of London, the former prime minister claimed that people voted in the referendum "without knowledge of the true terms of Brexit".
He urged "a way out from the present rush over the cliff's edge".
Former Tory leader Iain Duncan Smith said the comments were arrogant and undemocratic but Lib Dem Nick Clegg said he "agreed with every word".
Former UKIP leader Nigel Farage said Mr Blair was "yesterday's man" while Downing Street said it was "absolutely committed" to seeing Brexit through.
Foreign Secretary Boris Johnson added: "I urge the British people to rise up and turn off the TV next time Blair comes on with his condescending campaign."
Tony Blair calls for people to 'rise up' against Brexit - BBC News
He urged "a way out from the present rush over the cliff's edge".
Former Tory leader Iain Duncan Smith said the comments were arrogant and undemocratic but Lib Dem Nick Clegg said he "agreed with every word".
Former UKIP leader Nigel Farage said Mr Blair was "yesterday's man" while Downing Street said it was "absolutely committed" to seeing Brexit through.
Foreign Secretary Boris Johnson added: "I urge the British people to rise up and turn off the TV next time Blair comes on with his condescending campaign."
Tony Blair calls for people to 'rise up' against Brexit - BBC News