Hey, What I'm looking for are opinions, and why you think so. I know, I know, preventative action is best, but if you get one, now what? One school of thought is to use a "live cd", like BartPE, or a Linux live cd. I booted with BartPE, and ran the scans with a portable version of Clamwin from a thumbdrive. It detected and quaranteend some stuff, but not everything. I guess, the reason behind that is, there are no locked Windows files for malware to hide in. Makes for easier removal, but I don't know about detection. Another method is run in "safemode", and try to run the scans using your existing installed antivirus programs. That also works to some degree, but if you decide to use MalwareBytes,(which rocks by the way), it specifically says not to run it in safemode, but to run it when windows if fully up and running, so it's heuristics detection can work properly. Of course I have to ask which programs, or combination of programs do you think is best for malware removal? Thanks for the input.