Nanomachines which can drill into cancer cells, killing them in just 60 seconds, have been developed by scientists.
The tiny spinning molecules are driven by light, and spin so quickly that they can burrow their way through cell linings when activated.
In one test conducted at Durham University the nanomachines took between one and three minutes to break through the outer membrane of prostate cancer cell, killing it instantly.
The ‘motor’ is a rotor-like chain of atoms that can be prompted to move in one direction, causing the molecule to rotate at high speed.
Dr Robert Pal of Durham University said: “We are moving towards realising our ambition to be able to use light-activated nanomachines to target cancer cells such as those in breast tumours and skin melanomas, including those that are resistant to existing chemotherapy.
“Once developed, this approach could provide a potential step change in non-invasive cancer treatment and greatly improve survival rates and patient welfare globally.”
Motorised molecules that target diseased cells may deliver drugs or kill the cells by drilling into the cell membranes.Credit: Tour Group/Rice University
The scientists, whose work is reported in the journal Nature, created several different light-activated motorised molecules designed to home in on specific cells.
The molecules could be used either to tunnel into cells carrying therapeutic agents, or to act as killer weapons that blast open tumour membranes.
Videos showed the cancer cell membranes bubbling under the assault.
more
Nanomachines that drill into cancer cells killing them in just 60 seconds developed by scientists
The tiny spinning molecules are driven by light, and spin so quickly that they can burrow their way through cell linings when activated.
In one test conducted at Durham University the nanomachines took between one and three minutes to break through the outer membrane of prostate cancer cell, killing it instantly.
The ‘motor’ is a rotor-like chain of atoms that can be prompted to move in one direction, causing the molecule to rotate at high speed.
Dr Robert Pal of Durham University said: “We are moving towards realising our ambition to be able to use light-activated nanomachines to target cancer cells such as those in breast tumours and skin melanomas, including those that are resistant to existing chemotherapy.
“Once developed, this approach could provide a potential step change in non-invasive cancer treatment and greatly improve survival rates and patient welfare globally.”
Motorised molecules that target diseased cells may deliver drugs or kill the cells by drilling into the cell membranes.Credit: Tour Group/Rice University
The scientists, whose work is reported in the journal Nature, created several different light-activated motorised molecules designed to home in on specific cells.
The molecules could be used either to tunnel into cells carrying therapeutic agents, or to act as killer weapons that blast open tumour membranes.
Videos showed the cancer cell membranes bubbling under the assault.
more
Nanomachines that drill into cancer cells killing them in just 60 seconds developed by scientists
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