Megan Walker's family say a friendís bull mastiff cross went berserk when it heard barking on a Nintendo DS game.
It dragged Megan, nine, off a sofa as she played the virtual pet puppy game Nintendogs.
The dog sank its teeth into her face, bit her several times and ripped off her top lip.
Quick-thinking police officers put the piece of lip on ice and surgeons were able to sew it back on.
'I think this game should carry some kind of warning,' said the girlís grandma Jean Taylor.
'People should be told not to play it when there are dogs in the room. I blame the game for what happened to Megan. If they hadnít been playing it I donít think the dog would have gone for her.'
Megan was playing at a friendís house in Bolton when the accident happened. The dog, named Saracen, has since been put down.
Megan was taken by ambulance to Manchester Childrenís Hospital, where doctors managed to re-attach the lip.
Megan was in the care of her grandmother, Jean Taylor, while her mother Leanne Walker, aged 34, was on holiday in Jamaica for her birthday.
Mrs Taylor, aged 58, had allowed her granddaughter to stay at Ms Melvilleís house, as she is friends with her daughters.
Megan, a pupil at St Jamesí Primary School, had woken up and was turning on the game station at around 10am on Sunday, September 19, while Saracen was asleep on a mattress in the living of the house.
St Jamesí Primary School pupil Megan said: 'When I woke up I turned on the Nintendo. It barked and Saracen dragged me off the couch by my foot. I was scared.'
When she realised that Megan was being attacked, Ms Melville started kicking him and her second pet dog, named Zena, also attacked Saracen in a bid to save the child.
'When I saw her I went hysterical. She just had a dirty rag over her face. I just said Ďwhereís her lip?í It was horrible, the worse thing I have ever seen in my life,' said Mrs Taylor.
'The police went in the house and found the lip and brought it up to the hospital on ice.'
Megan was in surgery for two hours and spent five days in hospital. It is hoped that her lip will heal, though doctors will have a better idea when they take her bandage off on Wednesday.
Mrs Taylor said: 'Hopefully the surgery has worked or she could have to have more plastic surgery down the line. Sheís been so brave. She didnít cry once.'
She said that her daughter, who is still on holiday, knew about the incident but probably didnít realise just how bad it had been.
Inspector Phil Spurgeon said: 'This was a really nasty incident but one which falls outside of the law. The dog in question was not a banned breed and the incident happened in a private address, not in public.
'The owner signed the dog over for destruction and it has now been put down by a vet.'
Ms Melville was unavailable for comment, but it is understood that she told police that Megan may have kicked Saracen and that is why he attacked her.
No one from Nintendo was available for comment.
Read more: Girl's lip torn off by dog which heard barking on her Nintendo DS | Mail Online
Why can't people taker repsoblities for there mistakes? hum... lets blame teh gas company for my gas running out since i didn't feel it up all the way.
i am going to sue the news for getting me depress now emotional distress
first of this is a handheld system that is not a computer game.
How about watch kids and dogs supervison? how about.... thinking of going into another room where you can closed the door. how about... teaching the dog right or wrong manners. putting the dog was just as bad as animal cutlery.